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Lick a toad

Well while it might have happened to poor Homer, in reality it probably never happened, and if it did, there was was probably no high involved. Something not so nice might have happened though. So to bring chaos to order, this is what we are talking about. Psychoactive toad is a name that has been used for toads from which psychoactive substances from the family of bufotoxins can be derived. These substances serve the toad to protect itself and serves as its primary defense system.
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Licking Toads is no Fairytale: Side Effects and Dangers

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Why Licking Toads is no Fairytale: Side Effects and Dangers

If your idea of happily ever after involves an afternoon psychedelic trip, then you may think kissing a frog will lead you to your fairytale ending. But this fairy tale may have grim results. Right out of the gate there is an important distinction to make. Toads are a subcategory of frogs in the order Anura, meaning that every toad is a frog, but not every frog is a toad. Toads are the animal that secretes fabled hallucinogenic substances from their skin. Not every toad is an equal opportunity lick-victim either.
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Researchers list reasons not to lick a toad

Top definition. Toad Licking unknown. In reality there are no toads that will cause any person or animal to get "high" by licking them. There are however some species of toads known as " psychoactive toads" that produce a very powerful psychedelic tryptamine in their venom called 5-MeO-DMT a close relative to DMT. One cannot ingest the 5-MeO-DMT by licking a psychoactive toad; it would be destroyed in the stomach.
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January 27, As human diseases become alarmingly antibiotic resistant, identification of new pharmaceuticals is critical. The cane toad and other members of the Bufonidae family produce substances widely used in traditional folk medicine, but endangered family members, like Panama's golden frog, Atelopus zeteki , may disappear before revealing their secrets. Fifteen of 47 frog and toad species used in traditional medicine belong to the family Bufonidae.
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